| The Effect of Premedicants , Diazepam and Atropine Sulfate on Human Thyroxine Levels in Plasma. |
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Dong Kuk Kim, Ik Johng Sohn |
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Department of Anesthesiology, College of Medicine, Chosun University, Kwangju, Korea. |
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| Abstract |
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This study was undertaken to investigate the effect of premedicants, diazepam and atropine sulfate in ten surgical patients by determining human plasma thyroxine levels.
Tetrasorb-125 was utilized as a kit which offers a method for quantitative measurement of total circulating serum thyroxine. The plasma thyroxine level before administration of premedicants was 11. 16+/-2. 45ug/100ml and at 60 minutes after administration of premedicants. it was 11. 3+/-2.
73ug/100ml so that clinical significance of the result was absent. The number of male and female patients was 3 and 7, mean age 40. 1+/-9. 82 and average body weight 56. 1+/-4.
01kg. Consequently there was no significant change in human plasma thyroxine during one hour :of premedication. |
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