Korean J Anesthesiol Search


Korean J Anesthesiol > Volume 32(1); 1997 > Article
Korean Journal of Anesthesiology 1997;32(1):13-18.
DOI: https://doi.org/10.4097/kjae.1997.32.1.13   
The Effects of Superior Cervical Ganglion Block on the Behavioral Despair in Rats.
Chong Min Park, Jong Bun Kim, Hyeon Ja Kil
Department of Anesthesiology, Catholic University Medical College, Seoul, Korea.
The stellate ganglion block controls the pain and the vascular insufficiency in the innervating regions. Recently, the therapeutic indications of the stellate ganglion block are widely extended to the psychosomatic disorder. Therefore, this study was designed to observe the effect of the stellate ganglion block on stress using the Porsolt's behavioral despair model of rats.
Fifty-five male Sprague-Dawley rats were given five forced-swimming tests at 24-hour intervals. The first test through which rats learn helplessness lasted 15 minutes and following four tests given 30 minutes after every superior cervical ganglion block lasted 5 minutes respectively. The superior cervical ganglion block was achieved by using 0.2 ml of 1% lidocaine in the experimental group(n=30), and 0.2 ml of normal saline instead of lidocaine in the control group(n=25). The duration of mobility was measured during the first 5 minutes in all tests.
A difference was found between the control and the experimental group in the performance ratios after the superior cervical ganglion block(P<0.01), but the number of trials of the superior cervical ganglion block did not effect the duration of mobility.
These results suggest that the superior cervical ganglion block reduces the duration of immobility independently of the number of trials of the superior cervical ganglion block.
Key Words: Sympathetic nervous system; ganglion blockade; stellate ganglion block; stress
Share :
Facebook Twitter Linked In Line it
METRICS Graph View
  • 4 Crossref
  • 842 View
  • 3 Download


Browse all articles >

Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2023 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next