Korean J Anesthesiol Search

CLOSE


Korean Journal of Anesthesiology 1992;25(6):1129-1136.
DOI: https://doi.org/10.4097/kjae.1992.25.6.1129   
Cardiovascular Effects of Verapamil during Nalbuphine - Nitrous Oxide Anesthesia.
Jung Kil Chung, Jin Mo Kim, Sung Sik Kim, Jung Koo Lee, Jae Kyu Cheun
Department of Anesthesiology, Keimyung University School of Medicine, Taegu, Korea.
Abstract
Cardiovascualar effects of a verapamil infusion were investigated in six dogs given nalbuphine-nitrous anesthesia. Verapamil 0.2 mg/kg was given followed by an infusion of 3 and 6 mcg/kg per minute. Verapamil significantly reduced the systemic vascular resistanee index and mean arterial pressure. The decrease in afterload led to an increase in cardiac index, since was little change in myocardial contractility(LV dp/dt). Administration of calcium chloride, 20 mg/kg, did not reverse tbe hemodynamic effects of verapamil. The data indicate that in dogs verapamil be even in high concentrations, during nalbuphine-nitrous oxide anesthesia without serious adverse hemodynamic sequences.
Key Words: Nalbuphine; Verapamil; Hemodynamic


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next