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Korean Journal of Anesthesiology 1993;26(2):293-298.
DOI: https://doi.org/10.4097/kjae.1993.26.2.293   
Cardiovascular Effect of Lidocaine in Patients under Halothane , Enflurane and Diazepam Anesthesia.
Bong Ho Shin, Sang Hyun Gwak, Sung Su Chung, In Ho Ha
Department of Anesthesiology, Chonnam National University Medical School, College of Dentistry, Kwangju, Korea.
Abstract
To evaluate the cardiovascular effect of lidocaine and serum electrolytes during inhalational or intravenous anesthesia, thirty-two healthy patients were randomly divided into three groups and measured systolic pressure, diastolic pressure, mean pressure, heart rate and serum K+ and Na+ level were measured at 30 sec, l, 3, 6, 12 minutes after intravenous injection of lidocaine(1.5 mg/kg) during halothane-N2O-O2 or enflurane-N2O-O2 or diazepam-N2O-O2 anesthesia. In all 3 groups, the values of hemodynamic and serum electrolytes were not changed by 2% lidocaine. These results indicate that intravenous injection of lidocaine(1.5 mg/kg) to prevent undesirable reflexes and to prevent intracranial hypertension is a safe method without depression of hemodynamics.
Key Words: Anesthetics; halothane; enflurane; diazepam; local Anesthetics; lidocaine; Cardiovascular effect


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