The Effect of Transdermal Scopolamine Patch on Nausea and Vomiting after Epidural Injection of Morphine.

Lee,  Hee Joo; Moon,  Dong Eon; Suh,  Jae Hyun; Kim,  Sung Nyeun

doi:1994.27.1.54

Clinical Research Article

Korean Journal of Anesthesiology 1994;27(1):54-59.
DOI: https://doi.org/10.4097/kjae.1994.27.1.54

The Effect of Transdermal Scopolamine Patch on Nausea and Vomiting after Epidural Injection of Morphine.

Hee Joo Lee, Dong Eon Moon, Jae Hyun Suh, Sung Nyeun Kim

Department of Anesthesiology, Catholic University College of Medicine, Seoul, Korea.

Abstract

Sixty patients, undergoing major gynecologic surgery with lumbar epidural anesthesia, were randomly selected 32 patients to apply a transdermal scopolamine patch (Kimite MyoungMoon, Korea) on the skin behind one ear. We were divided into 2 groups. Control group; epidural morphine 4mg were given and not applied scopolamine patch. Experimental group; epidural morphine 4mg were given and applied transdermal scopolamine patch on the skin behind her ear at the night before surgery. They were followed up for 3 days postoperatively and statistical analysis was done. There was a significant (p<0.05) reduction in nausea and vomiting between experimental group and control group. There was no significant incresed incidence in scopolamine side effects. However, despite receiving transderrnal scopolamine patch there was still a high incidence (43.8%) of nausea and vomiting.

Key Words: Epidural morphine; Transdermal scopolamine; Nausea; Vomiting