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Korean Journal of Anesthesiology 1995;28(2):228-233.
DOI: https://doi.org/10.4097/kjae.1995.28.2.228   
The Analgesic Effect of Intraarticular Bupivacaine and Morphine after Arthroscopic Knee Surgery.
Sang Chul Lee, Hyun Sung Cho
Department of Anesthesiology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
The effects of intrarticular bupivacaine(20 ml, 0.25%), morphine(1 mg in 20 ml NaCl), or combination of the two(morphine 1 mg or 2 mg in 20 ml of 0.25% bupivacaine) on postoperative analgesia after arthroscopic knee surgery were studied in randomized, prospective, double-blind trial in ASA I-II patients receiving spinal anesthesia. The pain was assessed 1, 2, 3, 4, 5, 24 and 48 hours after procedure by the visual analogue pain scale(VAS) scores, and additional analgesic requirement was recorded. There was no significant difference in VAS scores and additional analgesic requirements among groups except 5 hours after procedure. Both parameters were significantly greater in the bupivacaine-only-treated group than in the other three groups at that time. It is suggested that we'd better use morphine 1 mg in normal saline without bupivacaine after arthroscopic knee surgery to get the desirable postoperative analgesic effect.
Key Words: Intraarticular; Morphine; Bupivacaine; Postoperative Analgesia; Arthroscopic knee surgery


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