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Korean Journal of Anesthesiology 1995;28(2):245-250.
DOI: https://doi.org/10.4097/kjae.1995.28.2.245   
Rapid Tracheal Intubation with High-dose Vecuronium.
Beum Jun Cho, Soon Ho Nam, Yang Sik Shin, Kwang Won Park
1Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
2Department of Anesthesiology, Aju University College of Medicine, Suwon, Korea.
For the rapid endotracheal intubation, the ideal neuromuscular blocking drug with short onset time, short duration and few side effects has so far not been found. Succinylcholine is still, inspite of its side-effects and contraindications, the standard drug of choice for rapid intubation. But, high-dose vecuronium as an alternative to succinylcholine for rapid intubation may be recommended. To compare the intubating conditions with that in succinylcholine, the onset and cardiovascular effects of high-dose vecuronium(0.3 mg/kg) were evaluated clinically with a scoring system. The results are as follows ; 1) High-dose vecuronium may provide an alternative means of achieving a rapid onset of neuromuscular blockade. 2) High-dose vecuronium shows minimal effects on cardiovascular system. In concluson, high-dose vecuronium as an alternative method for rapid endotracheal intubation may be recommended without any significant cardiovascular change if succinylcholine is contraindicated.
Key Words: Rapid endotracheal intubating conditions; Succinylcholine; High-dose vecuronium


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