| Clinical Evaluation of Anesthetic Management for Pheochromocytoma Following Prazosin Pre-treament . |
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Jung Suh Koo, Hyok Kwon Kwon, Ok Hyun Cho |
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Department of Anesthesiology, Dae Rim St. Mary's Hospital, Seoul, Korea. |
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| Abstract |
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Perioperative management of patients with pheochromocytoma is challenging. Accordingly, proper preoperative preparation is important. Prazosin, a selective alpha I blocker, may offer a potential advantage. This 54-year-old woman was treated with prazosin 2 mg, b.i.d. for 15 days and also with propranolol 20 mg, b.i.d. for a few days intermittently before the proposed surgery. Both symptoms and blood pressure were well controlled effectively. Induction of anesthesia was accomplished with nitrolingual spray, fentanyl 100 ug, 1% idocaine 50 mg, 2.5% thiopental sodium 200 mg, vecuronium 6 mg and 100% O2-enflurane. During the surgical and anesthetic procedure, the patient showed a reduced incidence of excessive blood-pressure variations and no arrhythmia was present except for supraventricular ectopic beats. Conclusively, we believe that careful preoperative preparation is recommended to minimize intraoperative hemodynamic dieturbances and their sequelae. |
| Key Words:
Pheochromocytoma; Preoperative preparation; Prazosin |
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