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Korean J Anesthesiol > Volume 24(4); 1991 > Article
Korean Journal of Anesthesiology 1991;24(4):821-825.
DOI: https://doi.org/10.4097/kjae.1991.24.4.821   
Effect of Furosemide on the Serum Concentration of Sodium and Osmolality after Transurethral Resection of Prostate .
Hi Seob Kim, Dae Hyun Jo, Myung Ae Lee
Department of Anesthesiology, National Medical Center, Seoul, Korea.
This study was undertaken to compare the effects of furosemide on the serum concentration of sodium and osmolality after transurethral prostatic resection(TURP) using cytal solution, and to determine the adequate time of administration of frurosemide. At the end of prostatic resection, 15 patients were allocated randomly to receive furosemide (furosemide group) and were compared with 15 patients without administration of furosemide (control group). There was no difference in mean serum concentation of sodium between two groups. Serum osmolality in furosemide group was significantly increased as compared with control group one hour after operation. So cytal solution used during staged TURP and short operation within one hour do not affect serum corcentration of sodium and administration of furosemide is not associated with a change in serum concentration of sodium. But furosemide meaningfully increases the serum osmolality and it is more effective to administer it with administration at the end of prostatic reseetion.
Key Words: Diuretic; furosemide; Cytal; Hyponatremia; Hyposmolality; TURP
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