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Korean J Anesthesiol > Volume 9(2); 1976 > Article
Korean Journal of Anesthesiology 1976;9(2):237-242.
DOI: https://doi.org/10.4097/kjae.1976.9.2.237   
A Clinical Study on Serum Cholinesterase & Clinical Manifestation of Acute Parathion Intoxication .
Soo Ja Chu, Jung Ok Kee
1Department of Anesthesiology, Mational Medical College, Seoul, Korea.
2Department of Biochemistry, Mational Medical College, Seoul, Korea.
Abstract
We observed the change of serum cholinesterase and clinical symptoms of acute parathion intoxication in I.C.U. of N.M.C. from 1975 Sep. to 1976 Oct. The results were as follows; 1. Serum choinesterase level of control group (55 cases) was l00. 53+/-13. 8 and range was 74~125 unit. 2. Serum cholinesterase level were reduced markedly below 10 units in 10 cases of severe parathion intoxication. 3. With adequate treatment PAM & atropine, serum cholinesteraee level rose steadly from 3 rd hospital day to 7 th hospital day and thereafter marked rising was noted remarkable improvement of respiratory symptoms. 4. In cases of low serum cholinestrsse level, sudden aggravation of general symptoms even death occurred and the symptoms & signs were correlated serum cholinesterase level.
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