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Korean J Anesthesiol > Volume 12(2); 1979 > Article
Korean Journal of Anesthesiology 1979;12(2):129-133.
DOI: https://doi.org/10.4097/kjae.1979.12.2.129   
Clinical Effects of Hydroxyzine Hydrochloride as a Premedicant .
Wyun Kon Park, Hung Kun Oh
Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
Hydroxyzine hydrochloride, a minor tranquilizer and a ataratic, was tested clinically for effectiveness as a premedicant separate dosages of 1 and 2 mg/kg. Each 30 patients were in the physical status class 1 and 2 by A.S.A. classification, and the age distribution was from 20 to 60 years. The following results were obtained. 1) Emotionally calm response was seen in 70% in the hydroxyzine 1 mg/kg (group 1), and in 93.3%, in the 2 mg/kg (group 2). 2) Mental alertness was seen in 86. 6% in group 1, and in 66. 6% in group 2. 3) Complications after premedication were chilling and shivering, hypertension, nausea, and headache, and were not serious. Therefore this premedication was satisfactory in most cases, especially in group 2.
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