Changes of the Erythrocyte Glutathione Reduetase Activity before nd after Anestbesia.

Lee,  Young Joo; Lee,  Choon Hi

doi:1977.10.1.29

Clinical Research Article

Korean Journal of Anesthesiology 1977;10(1):29-35.
DOI: https://doi.org/10.4097/kjae.1977.10.1.29

Changes of the Erythrocyte Glutathione Reduetase Activity before nd after Anestbesia.

¹Department of Biochemistry, College of Medicine, Seoul Nationl University, Seoul, Korea.
²Department of Anesthesiology, College of Medicine, Ewha Womans University, Seoul, Korea.

Abstract

Riboflavin is a constituent of coenzyme, FMN, FAD and its content varies according to the physiological and nutritional status. However, the measurement of its content is so disputable that a new technique to determine its content has been developed, done by determination of glutathione reductase activity in red blood cell hemolysate. With this technique, the effect of various anesthetic agents (ether, halothane, tetracaine) upon riboflavin metabolism has been studied by the authors. In conclusion, the effects of anesthetics upon riboflavin metabolism are insignificant.