Korean J Anesthesiol Search

CLOSE


Korean Journal of Anesthesiology 1986;19(3):238-245.
DOI: https://doi.org/10.4097/kjae.1986.19.3.238   
Effects of Induction on Changes of Intracranial Pressure and Vital Signs during General Anesthesia.
Heung Dae Kim, Dae Pal Park, III Sook Suh, Sun Ok Song, Byung Yearn Choi, Choong Bae Moon, Soo Ho Cho
1Department of Anesthesiology, College of Medicine, Yeungnam University, Taegu, Korea.
2Department of Neurosurgery, College of Medicine, Yeungnam University, Taegu, Korea.
Abstract
It is true that intracranial pressure(ICP) and mean arterial pressure(MAP) are increased by induction of conventional inhalation general anesthesia, and it may be very dangerous in neurosurgical patients who had increased ICP. Therefore, this study was performed to know the ranges of ICP and MAP increase during induction of the general anesthesia with laryngoscopy and endotracheal intubation following thiopental sodium(4mg/kg) and succinyeholine chioride(1 mg/kg) injections in 16 neurosurgical patients with normal pulmonary and cardiac functions. All the patients were monitored ICP and intraarterial pressure preoperatively, and intracranial compliance, ICP, MAP and pulse rate were measured in all patients during induction of general anesthesia. The results were as follows: 1) Intracranial compliance; ICP during endotracheal intubation increased by 2 mmHg in those patients with pre-operatively normal range of compliance, but in those patients with compliance range of 2-3 ml/CmH2O, mean ICP increase was 5. 6+/-2. 45 mmHg, and in those patients with compliance range of 4-6 ml/CmH2O, it was 13. 010. 23 mmHg. 2) Mean ICP increased from 13.5+/-6.16 mmHg at pre-induction to-20.4+/-10.02 mmHg during endotracheal intubation, but it was not statistically significant(p>0.05) because the rate of ICP increase was not remarkable by endotracheal intubation in the patients without ICP increase in pre-induction. 3) Mean arterial pressure increased significantly from 116.71+/-6.65 mmHg at pre-induction to 160. 3+/-34. 24 mmHg during endotracheal intubation(P<0.05). 4) Pulsse rate increased significantly from 94.8+/-20.28 beat/min to 120.5+/-15.93 beat/min(p<0.001). 5) Cerebral perfusion pressure increased from 103.3+/-14.49mmHg 137.3+/- 35.91mmHg(p<0.025). It is stressed that certain procedures are necessary to prevent from further increase of ICP due to induction of general anesthesia in patient with increased ICP.


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
(서울특별시 마포구 마포대로 109 롯데캐슬 프레지던트 101동 3503호)
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                
Business Name: Korean Society of Anesthesiologists (대한마취통증의학회)
Business Registration: 106-82-07194
Representative: Jun Heum Yon (연준흠)

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next