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Korean J Anesthesiol > Volume 20(1); 1987 > Article
Korean Journal of Anesthesiology 1987;20(1):18-21.
DOI: https://doi.org/10.4097/kjae.1987.20.1.18   
Effect of Halothane , Enflurane and Nitrous Oxide-Thalamonal Aneathesia on Bleeding Time .
Young Seok Lee, Young Jo Lee, Jin Ho Kim, Jong Rae Kim, Chung Hyun Cho
Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
30 patients were randomly divided into three groups : halothane in oxygen(N=10) ; enflurane in oxygen(N= 10) ; Thalamonal plus nitrous oxide in oxygen(N= 10). Standardized bleeding time was measured using Ivy method before and at leaat 40 min after the induction of anesthesia. Arterial pressure was maintained at+/- 200 of control values and tem-perature was kept at 35~37 degrees C. The bleeding time was prolonged by 58% in the halothane group (P<0.001). There was essentially no change in bleeding time in the groups receiving enflurane and nitrous oxide-Thalamonal group, although there was considerable variability within each group, which did not seem to be related to differences in sex, age, type of surgery, concentration of agent used or surgical procedure. In conclusion, our resultg suggest that halothane may be contraindicated in situations where optimal hemostasis is critical.
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