Korean J Anesthesiol Search

CLOSE


Korean J Anesthesiol > Volume 56(6); 2009 > Article
Korean Journal of Anesthesiology 2009;56(6):639-645.
DOI: https://doi.org/10.4097/kjae.2009.56.6.639   
The optimal effect site concentration of remifentanil for tracheal intubation without muscle relaxant during inhalation anesthetic induction using sevoflurane in adult.
Hyun Jin Oh, Yoon Hee Kim, Jung Un Lee
1Department of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, Daejeon, Korea. yhkim0404@cnu.ac.kr
2Department of Anesthesiology and Pain Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
BACKGROUND
Sevoflurane has been shown to be suitable for inhalation induction of anesthesia in adults. The addition of remifentanil during sevoflurane induction allows for rapid and smooth tracheal intubation without muscle relaxant. The high concentration of remifentanil can result in improved conditions for tracheal intubation but also caused a cardiovascular instability. We tried to estimate optimal effect site concentration of remifentanil for tracheal intubation without muscle relaxants during inhalation anesthetic induction with 8 vol% sevoflurane and 50% N2O.
METHODS
One hundred five ASA I and II patients were randomly allocated to receive an effect site concentration of remifentanil 2, 4, or 6 ng/ml. Trachea was intubated without muscle relaxant after 3 minutes of inhalation induction with 8 vol% sevoflurane and 50% N2O. The intubating conditions for tracheal intubation were assessed and blood pressure and heart rate were recorded at the baseline, before intubation, just after intubation, 1, and 3 minute after intubation.
RESULTS
Tracheal intubation was successful in all patients. Clinically acceptable intubation conditions were 60%, 94%, and 100% in 2 ng/ml, 4 ng/ml, and 6 ng/ml group respectively. However, the number of patient who requested rescue medication for bradycardia in 6 ng/ml group was significantly higher than that in the other group (P < 0.05).
CONCLUSIONS
We concluded that 4 ng/ml effect site concentration of remifentanil is adequate concentration for tracheal intubation without muscle relaxants during inhalation induction using sevoflurane.
Key Words: Muscle relaxants; Remifentanil; Sevoflurane; Tracheal intubation


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
Room 1006 Yong-Seong BIZTEL Building, 109, Hangang-daero, Yongsan-gu, Seoul 04376, Korea
Tel: +82-2-795-5129    Fax: +82-2-792-4089    E-mail: anesthesia@kams.or.kr                

Copyright © 2019 by Korean Society of Anesthesiologists. All rights reserved.

Developed in M2community

Close layer
prev next