Korean Journal of Anesthesiology

Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial: Li-Kai Wang, Yao-Tsung Lin, Jui-Tai Chen, Winnie Lan, Kuo-Chuan Hung, et al.; Korean J Anesthesiol. 2023;76(4):280-289.

Review Article

February 24, 2023

Hemodynamic management during off-pump coronary artery bypass surgery: a narrative review of proper targets for safe execution and troubleshooting

Jae-Kwang Shim, Kwang-Sub Kim, Pierre Couture, André Denault, Young-Lan Kwak, et al.

Korean J Anesthesiol. 2023;76(4):267-279.

Off-pump coronary surgery requires mechanical cardiac displacement, which results in bi-ventricular systolic and diastolic dysfunction. Although transient, subsequent hemodynamic deterioration can be associated with poor prognosis and, in extreme cases, emergency conversion to on-pump surgery, which is associated with high morbidity and mortality. Thus, appropriate decision-making regarding whether the surgery can be proceeded based on objective hemodynamic targets is essential before coronary arteriotomy. For adequate hemodynamic management, avoiding myocardial oxygen supply-demand imbalance, which includes maintaining mean arterial pressure above 70 mmHg and preventing an increase in oxygen...

Clinical Research Article

December 5, 2022

Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial

Li-Kai Wang, Yao-Tsung Lin, Jui-Tai Chen, Winnie Lan, Kuo-Chuan Hung, et al.

Korean J Anesthesiol. 2023;76(4):280-289.

Background: Shared decision making using patient decision aids (PtDAs) was established over a decade ago, but few studies have evaluated its efficacy in Asian countries. We therefore evaluated the application of PtDAs in a decision conflict between two muscle relaxant reversal agents, neostigmine and sugammadex, and sequentially analyzed the regional differences and operating room turnover rates. Methods: This multicenter, outcome-assessor-blind, randomized controlled trial included 3,132 surgical patients from two medical centers admitted between March 2020 and August 2020. The patients were randomly divided into the classical and PtDA groups for pre-anesthesia...

Clinical Research Article

December 5, 2022

Learning curve of fiberoptic bronchoscope-guided tracheal intubation through supraglottic airway device for pediatric airway management: a manikin study

Sang-Hwan Ji, Sung-Ae Cho, Young-Eun Jang, Eun-Hee Kim, Jin-Tae Kim, et al.

Korean J Anesthesiol. 2023;76(4):290-299.

Background: Although fiberoptic-guided endotracheal intubation using a supraglottic airway device (SAD) is a good alternative for the management of difficult airways, its learning curve for residents has not been evaluated in pediatric patients. We aimed to train residents using a pediatric manikin and obtain learning curves to evaluate the efficiency of the training. Methods: We conducted a single-armed prospective study with anesthesiology residents. Plain endotracheal tube (ETT) intubation guided by a fiberoptic bronchoscope through Ambu® AuraGainTM was demonstrated in a pediatric manikin to the participants before training. The procedure was divided...

Clinical Research Article

December 28, 2022

Comparison of fiberoptic bronchoscopic intubation using silicone and polyvinyl chloride double-lumen tubes

Seyoon Kang, Yun Jeong Chae, Dae Hee Kim, Taek Geun Kim, Ji Young Yoo

Korean J Anesthesiol. 2023;76(4):300-306.

Background: Direct insertion of a double-lumen tube (DLT) using a flexible fiberoptic bronchoscope (FOB) is an option for DLT intubation. The difficult process of fiberoptic intubation is that the different properties of polyvinyl chloride and silicone DLTs may affect railroading differently. Therefore, we aimed to compare intubation using polyvinyl chloride and silicone DLTs over an FOB. Methods: Patients aged 19–75 years who required one-lung ventilation under general anesthesia were enrolled in this study. After induction of anesthesia, the anesthesiologist intubated the DLT using FOB. The primary outcome was the difficulty of railroading over the flexible FOB scaled into five grades (I, II-1, II-2, III, and IV). Additionally, the intubation time...

Clinical Research Article

February 3, 2023

Intravenous versus perineural dexmedetomidine as adjuvant in adductor canal block for total knee arthroplasty

Maha Ahmed Abo-Zeid Salim, Sherine Bakrey, Rania Elmohamady Elbadrawy

Korean J Anesthesiol. 2023;76(4):307-316.

Background: The shivering effect after spinal anesthesia in total knee arthroplasty (TKA) is challenging for anesthesiologists. This study aimed to compare two administration routes of dexmedetomidine as a post-neuraxial shivering prevention measure and an adjunctive analgesic and sedative agent. Methods: Fifty-six patients were randomly allocated into two equal groups. The intravenous dexmedetomidine (IV dex) group received an IV infusion of 0.5 µg/kg dexmedetomidine diluted in 20 ml saline and an adductor canal block (ACB) consisting of 20 ml of 0.25% levobupivacaine and 1 ml saline. The adductor canal block dexmedetomidine (ACB dex) group received a 20 ml IV infusion of saline and an ACB consisting of 20 ml 0.25% levobupivacaine and...

Clinical Research Article

March 14, 2023

Modified pectoral nerve block versus bi-level erector spinae plane block for postoperative analgesia after radical mastectomy surgery: a prospective, randomized, controlled trial

Sevim Cesur, Can Aksu, Sertaç Ata Güler, Alparslan Kuş

Korean J Anesthesiol. 2023;76(4):317-325.

Background: Regional anesthesia techniques constitute an important part of successful analgesia strategies in the perioperative care of patients undergoing breast surgery. The advent of ultrasound-guided regional anesthesia has led to the development of fascial plane blocks. The large array of blocks available for postoperative analgesia in breast surgery has increased the accessibility of regional anesthesia but has also created a dilemma of choice. This study compared the analgesic efficacy of the ultrasound-guided modified pectoral nerve (PECS) block and erector spinae plane block (ESPB) in patients undergoing radical mastectomy. Methods: Seventy women...

Clinical Research Article

January 12, 2023

Erector spinae plane versus fascia iliaca block after total hip arthroplasty: a randomized clinical trial comparing analgesic effectiveness and motor block

Edoardo Flaviano, Silvia Bettinelli, Maddalena Assandri, Hassam Muhammad, Alberto Benigni, et al.

Korean J Anesthesiol. 2023;76(4):326-335.

Background: Ultrasound-guided supra-inguinal fascia iliaca block (FIB) provides effective analgesia after total hip arthroplasty (THA) but is complicated by high rates of motor block. The erector spinae plane block (ESPB) is a promising motor-sparing technique. In this study, we tested the analgesic superiority of the FIB over ESPB and associated motor impairment. Methods: In this randomized, observer-blinded clinical trial, patients scheduled for THA under spinal anesthesia were randomly assigned to preoperatively receive either the ultrasound-guided FIB or ESPB. The primary outcome was morphine consumption 24 h after surgery. The secondary outcomes...

Clinical Research Article

December 28, 2022

Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study

Kwon Hui Seo, Ji Hyung Hong, Mi Hyoung Moon, Wonjung Hwang, Sea-Won Lee, et al.

Korean J Anesthesiol. 2023;76(4):336-347.

Background: Propofol-based total intravenous anesthesia (TIVA) improves long-term outcomes after cancer surgery compared with inhalation anesthesia. However, its effect on patients undergoing non-small cell lung cancer (NSCLC) surgery remains unclear. We aimed to compare the oncological outcomes of TIVA and inhalation anesthesia after curative resection of early-stage NSCLC. Methods: We analyzed the medical records of patients diagnosed with stage I or II NSCLC who underwent curative resection at a tertiary university hospital between January 2010 and December 2017. The primary outcomes were recurrence-free survival (RFS) and overall survival (OS) according...

Clinical Research Article

January 26, 2023

Association of the perfusion index with postoperative acute kidney injury: a retrospective study

Pyoyoon Kang, Jung-bin Park, Hyun-Kyu Yoon, Sang-Hwan Ji, Young-Eun Jang, et al.

Korean J Anesthesiol. 2023;76(4):348-356.

Background: Many studies have examined the risk factors for postoperative acute kidney injury (AKI), but few have focused on intraoperative peripheral perfusion index (PPI) that has recently been shown to be associated with postoperative morbidity and mortality. Therefore, this study aimed to evaluate the relationship between intraoperative PPI and postoperative AKI under the hypothesis that lower intraoperative PPI is associated with AKI occurrence. Methods: We retrospectively searched electronic medical records to identify patients who underwent surgery at the general surgery department from May 2021 to November 2021. Patient baseline characteristics, pre- and post-operative laboratory test results, comorbidities, intraoperative vital signs, and discharge profiles were obtained from the Institutional Clinical Data Warehouse...

Experimental Research Article

April 4, 2023

Effects of remote ischemic postconditioning on hepatic injury in lipopolysaccharide-induced endotoxemic rats

Jin Duck Cho, Hoon Jung, Jeong Eun Lee, Eun Kyung Choi, Hyun Ah Kim, et al.

Korean J Anesthesiol. 2023;76(4):357-367.

Background: Remote ischemic postconditioning (RIPoC) is induced by several cycles of brief, reversible, mechanical blood flow occlusion, and reperfusion of the distal organs thereby protecting target organs. We investigated if RIPoC ameliorated liver injury in a lipopolysaccharide (LPS)-induced endotoxemic rats. Methods: Protocol 1) Rats were administered LPS and samples collected at 0, 2, 6, 12, and 18 h. 2) After RIPoC at 2, 6, and 12 h (L+2R+18H, L+6R+18H, and L+12R+18H), samples were analyzed at 18 h. 3) RIPoC was performed at 2 h, analysis samples at 6, 12, 18 h (L+2R+6H, L+2R+12H, L+2R+18H), and RIPoC at 6 h, analysis at 12 h (L+6R+12H). 4) Rats were assigned to a control...

Experimental Research Article

November 15, 2022

Lipid emulsion inhibits the cardiac toxicity caused by chloroquine via inhibition of reactive oxygen species production

Soo Hee Lee, Seong-Ho Ok, Seung Hyun Ahn, Gyujin Sim, Hyun-Jin Kim, et al.

Korean J Anesthesiol. 2023;76(4):368-382.

Background: Lipid emulsion (LE) is effective in treating intractable cardiac depression induced by the toxicity of highly lipid-soluble drugs including local anesthetics. However, the effect of LE on chloroquine (CQ)-evoked cardiac toxicity remains unclear. This study aimed to examine the effect of Lipofundin MCT/LCT, an LE, on the cardiotoxicity caused by CQ in H9c2 rat cardiomyoblasts and elucidate the underlying cellular mechanism. Methods: The effects of CQ (1 × 10-4 M), LE, and the reactive oxygen species (ROS) scavengers mitotempo and N-acetyl-L-cysteine (NAC), alone or combined, on cell viability and...

From evidence-based medicine to patient-centered care Woong Mo Kim Korean J Anesthesiol. 2023;76(4):265-266. Editorial July 27, 2023 Full text PubReader ePub PDF	Hemodynamic management during off-pump coronary artery bypass surgery: a narrative review of proper targets for safe execution and troubleshooting Jae-Kwang Shim, Kwang-Sub Kim, Pierre Couture, André Denault, Young-Lan Kwak, Kyung-Jong Yoo, Young-Nam Youn Korean J Anesthesiol. 2023;76(4):267-279. Review Article February 24, 2023 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial Li-Kai Wang, Yao-Tsung Lin, Jui-Tai Chen, Winnie Lan, Kuo-Chuan Hung, Jen-Yin Chen, Kuei-Jung Liu, Yu-Chun Yen, Yun-Yun Chou, Yih-Giun Cherng, et al. Korean J Anesthesiol. 2023;76(4):280-289. Clinical Research Article December 5, 2022 Cited By 2 Full text PubReader ePub PDF PDF(Korean) Supplementary Material	Learning curve of fiberoptic bronchoscope-guided tracheal intubation through supraglottic airway device for pediatric airway management: a manikin study Sang-Hwan Ji, Sung-Ae Cho, Young-Eun Jang, Eun-Hee Kim, Jin-Tae Kim, Hee-Soo Kim, Ji-Hyun Lee Korean J Anesthesiol. 2023;76(4):290-299. Clinical Research Article December 5, 2022 Full text PubReader ePub PDF PDF(Korean)
Comparison of fiberoptic bronchoscopic intubation using silicone and polyvinyl chloride double-lumen tubes Seyoon Kang, Yun Jeong Chae, Dae Hee Kim, Taek Geun Kim, Ji Young Yoo Korean J Anesthesiol. 2023;76(4):300-306. Clinical Research Article December 28, 2022 Full text PubReader ePub PDF PDF(Korean)	Intravenous versus perineural dexmedetomidine as adjuvant in adductor canal block for total knee arthroplasty Maha Ahmed Abo-Zeid Salim, Sherine Bakrey, Rania Elmohamady Elbadrawy Korean J Anesthesiol. 2023;76(4):307-316. Clinical Research Article February 3, 2023 Full text PubReader ePub PDF PDF(Korean)
Modified pectoral nerve block versus bi-level erector spinae plane block for postoperative analgesia after radical mastectomy surgery: a prospective, randomized, controlled trial Sevim Cesur, Can Aksu, Sertaç Ata Güler, Alparslan Kuş Korean J Anesthesiol. 2023;76(4):317-325. Clinical Research Article March 14, 2023 Full text PubReader ePub PDF PDF(Korean)	Erector spinae plane versus fascia iliaca block after total hip arthroplasty: a randomized clinical trial comparing analgesic effectiveness and motor block Edoardo Flaviano, Silvia Bettinelli, Maddalena Assandri, Hassam Muhammad, Alberto Benigni, Gianluca Cappelleri, Edward Rivera Mariano, Luca Ferdinando Lorini, Dario Bugada Korean J Anesthesiol. 2023;76(4):326-335. Clinical Research Article January 12, 2023 Full text PubReader ePub PDF PDF(Korean)
Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study [commentary-article] Kwon Hui Seo, Ji Hyung Hong, Mi Hyoung Moon, Wonjung Hwang, Sea-Won Lee, Jin Young Chon, Hyejin Kwon, Sook Hee Hong, Sukil Kim Korean J Anesthesiol. 2023;76(4):336-347. Clinical Research Article December 28, 2022 Cited By 1 Full text PubReader ePub PDF PDF(Korean)	Association of the perfusion index with postoperative acute kidney injury: a retrospective study Pyoyoon Kang, Jung-bin Park, Hyun-Kyu Yoon, Sang-Hwan Ji, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Hyung Chul Lee, Jin-Tae Kim, Hee-Soo Kim Korean J Anesthesiol. 2023;76(4):348-356. Clinical Research Article January 26, 2023 Cited By 1 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Effects of remote ischemic postconditioning on hepatic injury in lipopolysaccharide-induced endotoxemic rats Jin Duck Cho, Hoon Jung, Jeong Eun Lee, Eun Kyung Choi, Hyun Ah Kim, Hyun-Su Ri, Hyunjee Kim, Ji Young Park, Kyung-Hwa Kwak, Dong Gun Lim Korean J Anesthesiol. 2023;76(4):357-367. Experimental Research Article April 4, 2023 Full text PubReader ePub PDF PDF(Korean)	Lipid emulsion inhibits the cardiac toxicity caused by chloroquine via inhibition of reactive oxygen species production Soo Hee Lee, Seong-Ho Ok, Seung Hyun Ahn, Gyujin Sim, Hyun-Jin Kim, Mingu Kim, Sangcheol Yoon, Ju-Tae Sohn Korean J Anesthesiol. 2023;76(4):368-382. Experimental Research Article November 15, 2022 Cited By 1 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Catatonia associated with prolonged stupor after general anesthesia in a patient with multiple neuropsychiatric disorders -a case report- Sungwon Baek, Min Hee Heo, Kyung Woo Kim, Sang Il Lee, Kyung-Tae Kim, Jang Su Park, Won Joo Choe, Jun Hyun Kim, Ji Yeon Kim Korean J Anesthesiol. 2023;76(4):383-388. Case Report March 14, 2023 Full text PubReader ePub PDF	Ultrasound-guided radiofrequency denervation and pericapsular nerve group block for chronic hip joint pain in a patient diagnosed with Duchenne muscular dystrophy Gokhan Yildiz, Muge Baran, Saziye Sahin, Erkan Yavuz Akcaboy, Seref Celik Korean J Anesthesiol. 2023;76(4):389-390. Letter to the Editor March 21, 2023 Full text PubReader ePub PDF
Comment on "Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study" Rohan Magoon, Devishree Das, Jes Jose Korean J Anesthesiol. 2023;76(4):390-391. Letter to the Editor February 9, 2023 Full text PubReader ePub PDF	General anesthesia using remimazolam and remifentanil in combination with local anesthetics without neuromuscular blocking agents in a patient with myotonic dystrophy Yukihide Koyama, Haruko Nishikawa, Yoriko Murase, Kei Morita, Koichi Tsuzaki Korean J Anesthesiol. 2023;76(4):391-393. Letter to the Editor March 28, 2023 Full text PubReader ePub PDF