In our facility, 45 patients regularly undergo PD in an outpatient setting. Of these, 14 (31%) patients use icodextrin as the dialysate.

Classically, glucose oxidase is used in bedside glucometers. A major drawback is its cross-reactivity with dioxygen, resulting in an underestimation of the blood glucose. As an alternative, soluble quinoprotein glucose dehydrogenase (GDH) with the co-factor pyrroloquinoline quinone (sPQQ-GDH) was developed. This enables measurements without any interference from dioxygen, although low substrate specificity and cross-reactivity with maltose, a metabolite of icodextrin, have been reported. A group of Japanese researchers discovered a novel thermostable heme-containing flavin adenine dinucleotide (FAD)-GDH with high substrate specificity [4]. A FAD-GDH-dependent bedside glucometer is now available commercially, and the list of glucometers is available from the website of Baxter. In May 2015, all of the glucometers in our hospital were replaced and no problems have occurred since then. The cost of the tips for glucometer does not substantially differ from those of sPQQ-GDH glucometer.