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Korean Journal of Anesthesiology 2004;46(4):430-433.
DOI: https://doi.org/10.4097/kjae.2004.46.4.430   
Relationship Between Pain Threshold and Postoperative Morphine Requirement.
Dae Hyun Kim, Kook Hyun Lee, Dae Soon Cho, Hae Jeong Jeong, Ji Hee Kim, Soon Ae Lee, Ji Yoon Rho, Hong Ki Min, Jung Hee Ryu
Department of Anesthesiology and Pain Medicine, National Cancer Center, Seoul, Korea, *Department of Anesthesiology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
BACKGROUND
Variability in pain sensitivity is a well known phenomenon. The variability also extends to experimental stimuli and postoperative opioid requirement. But the report of the relationship between pain threshold and postoperative opioid requirement is very rare.
METHODS
We investigated prospectively the association between pressure pain threshold and postoperative morphine requirement. We estimated pressure pain threshold by using pressure algometer and adopted PCA to treat postoperative pain.
RESULTS
In this study the relationship between pain threshold and postoperative opioid requirement was significant. But the correlation was weak negative (Pearson r = -0.273, P < 0.05).
CONCLUSIONS
Considering other associated factors which affect postoperative pain, although correlation between pain threshold and postoperative opioid requirement was significant but we concluded that clinical relevance of pain threshold is uncertain.
Key Words: pressure pain threshold; postoperative morphine requirement


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