Comparison of Intravenous Administration and Surgical Site Infiltration of Ketorolac Combined with Preincisional Infiltration of Bupivacaine. |
Dong Hee Kim, Sang Yoon Lee, Seok Kon Kim, Gwan Woo Lee, Bong Jin Kang, Hyun Yang Oh, Choong Hak Park |
1Department of Anesthesiology, College of Medicine, Dankook University, Cheon An, Korea. 2Department of Obstetric and Gynecology, College of Medicine, Dankook University, Cheon An, Korea. |
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Abstract |
BACKGROUND We postulated that ketorolac as a component of surgical site infiltration would result in better analgesia than intravenous ketorolac. METHODS Sixty patients who scheduled for elective total abdominal hysterectomy received ketorolac 60 mg (2 ml) either via surgical site infiltration directly (n=30) or parenteral route (n=30) with surgical site infiltration of 0.25% bupivacaine 18 ml 20 min before skin incision. RESULTS Postoperative analgesic requirement, 48 hour total infusion dose and first 12 hour infusion dose of PCA fentanyl, were significantly lower in surgical site group.
There were no significant differences in VAS score and side effects between two groups. CONCLUSION Ketorolac improves analgesia when it is administered in the surgical site. |
Key Words:
Analgesia: postoperative; Analgesics: ketorolac; Anesthetic techniques: infiltration; intravenous |
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